搜索结果

Search Results for " dna polymerase beta "

Targets Recommended: DNA/RNA Synthesis Antibacterial Antibiotic

抑制剂 & 化合物

天然产物

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T1154	Rifaximin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifaximin 是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
T25084	AM-TS23 AM TS23
	AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.

化合物

Rifaximin

Cat.No: T1154

Synonym:

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat. No.	Product Name	Target	Signaling Pathways
T3376	Cynaroside 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside	Others; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Cynaroside (Luteolin 7-O-Glucoside) 是一个抗氧化类黄酮。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 32 nM。
TN5879	Edgeworin
	Edgeworin is a DNA polymerase beta (pol beta) inhibitor, it inhibits both the lyase and polymerase activities of DNA polymerase beta; it can potentiate the inhibitory action of the anticancer drug bleomycin in cultured A549 cells via an inhibition of DNA
TN6148	3-O-trans-p-Coumaroylmaslinic acid
	3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B" inhibitor. It shows antimicrobial activity on Gram-positive bacteria and yeasts.

天然产物

Cynaroside

Cat.No: T3376

Synonym: 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside

Target: Others, Influenza Virus, DNA/RNA Synthesis

3-O-trans-p-Coumaroylmaslinic acid

Cat.No: TN6148

Synonym:

Target:

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00792	DNA PolymeraseBeta Protein, Human, Recombinant (His) DNA Polymeraseβ,POLB,DNA Poly...	Human	E. coli
	Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. It conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a proce...
TMPH-00427	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant DNA polymerase IV,dinB,Pol IV	Colwellia psychrerythraea	E. coli
	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant is expressed in E. coli expression syste...
TMPH-00426	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His) dinB,DNA polymerase IV,Pol IV	Colwellia psychrerythraea	E. coli
	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli expression...